Jill Scott, Erykah Badu, Joe Sample, George Duke, Christian Mc Bride, and Stevie Wonder made guest appearances.
In 2008, Latifah was asked if she would make another hip-hop album.
She played the role of Thelma in the 1999 movie The Bone Collector, alongside Denzel Washington and Angelina Jolie.
The following year, in 2009, she released her album Persona.
The song "Cue the Rain" was released as the album's lead single. In January 2012, while appearing on 106 & Park with Dolly Parton, to promote Joyful Noise, Latifah stated that she had been working on a new album.
From 1993 to 1998, Latifah had a starring role on Living Single, the FOX sitcom, which gained high ratings among black audiences; she also wrote and performed its theme music. She began her film career in supporting roles in the 19 films House Party 2, Juice and Jungle Fever.
Her third album Black Reign (1993), spawned the single "U. Latifah gained mainstream success and acclaim with her performance in the film Chicago (2002), receiving an Academy Award nomination for Best Supporting Actress.
Latifah released her fifth album The Dana Owens Album in 2004.
She also had recurring roles during the second season (1991–1992) of the NBC hit The Fresh Prince of Bel-Air.